LA BioMed Spotlight on Clinical Trials

The Long-Term Oxygen Treatment Trial (LOTT)

Brief Summary: The purpose of the study is to determine whether or not oxygen treatment helps individuals who suffer from certain types of Chronic Obstructive Pulmonary Disease (COPD). The LOTT study is testing the usefulness of oxygen treatment for COPD patients who have low oxygen saturation at rest and those who have normal saturation at rest but low oxygen during exercise. While many studies have already shown that oxygen improves life expectancy and quality of life in COPD patients with very low oxygen levels, the goal is to find out whether or not oxygen treatment benefits patients with mild to moderate hypoxemia and COPD.

Sponsored by the National Heart, Lung and Blood Institute of the National Institutes of Health, this research study began enrolling patients in January 2009 and will continue following patients until May 2013.

For additional information on how to enroll in the LOTT study, please contact Peggy Walker atpwalker@labiomed.org.

Statins in COPD Exacerbations (STATCOPE)

Brief Summary: This trial is designed to determine if statins can reduce the number and severity of COPD exacerbations in patients who are at risk for flare-ups. Flare-ups are occasional bad periods lasting hours, days, or even weeks where patients suffer from symptoms such as coughing, wheezing, shortness of breath, etc. The study is important because although statins are already used by millions of people with heart disease, they do have side effects. This trial will carefully weigh the risks and benefits of a once-a-day dose of statin over a three-year period.

This study is sponsored by the National Heart Lung & Blood Institute (NHLBI) COPD Clinical Research Network (CCRN).

For additional information on how to enroll in the STATCOPE study, please contact Kathleen Norulak atknorulak@labiomed.org

For a complete listing of LA BioMed clinical studies, including all studies on chronic lung disease, please visitwww.clinicaltrials.gov.